Papers

Stay up-to-date with our most recent publications

Papers

2023

Sánchez-Magraner, L., Gumuzio, J., et al. Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non–Small-Cell Lung Cancer. Journal of Clinical Oncology. 2023.

2022

Miles, J., et al. Determination of Interactive States of Immune Checkpoint Regulators in Lung Metastases after Radiofrequency Ablation. MDPI Cancers. 2022.

2021

Sanchez-Magraner, L. Quantification of PD-1/PD-L1 Interaction between Membranes from PBMCs and Melanoma Samples Using Cell Membrane Microarray and Time-Resolved Förster Resonance Energy Transfer. Analytica. 2021.

Bortolomeazzi, M., et al. Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts. Gastroenterology. 2021.

Larijani, B., et al. Quantification of Biomarker Functionality Predicts Patient Outcomes. British Journal of Cancer. 2021.

2020

Sanchez-Magraner, L., Miles, J., et al. High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to anti-PD-1/PD-L1 Treatment. Cancer Research. 2020.

2019 - 2014

Miles, J., et al. Time Resolved amplified FRET Identifies Protein Kinase B Activation State as a Poor Prognostic Marker in Clear Cell Renal Cell Carcinoma. BBA Clinical. 2017

Veeriah, S., et al. High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer. Cancer Research. 2014.

Reviews

Miles, J., et al. The Fusion of Quantitative Molecular Proteomics and Immune-Oncology: A Step Towards Precision Medicine in Cancer Therapeutics. FEBS Letters. 2022.

Larijani, B., and Miles, J. Quantification of Protein-Protein Interactions and Activation Dynamics: A New Path to Predictive Biomarkers. Biophysics Chemistry. 2022.

Why HAWK?

Learn why we are the best spatial biology choice for translating protein function research into real clinical value for patients. Our combination of unrivalled precision and dynamic range allows us to establish robust clinical cut offs to advance your research.

What is QF-Pro®?

Learn about Quantifying Functions in Proteins (QF-Pro®) and how our advanced bio-imaging assay can further your research outputs. Find out about how QF-Pro® works and understand which protein functional events it can quantify.