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Sánchez-Magraner, L., Gumuzio, J., et al. Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non–Small-Cell Lung Cancer. Journal of Clinical Oncology. 2023.


Miles, J., et al. Determination of Interactive States of Immune Checkpoint Regulators in Lung Metastases after Radiofrequency Ablation. MDPI Cancers. 2022.


Sanchez-Magraner, L. Quantification of PD-1/PD-L1 Interaction between Membranes from PBMCs and Melanoma Samples Using Cell Membrane Microarray and Time-Resolved Förster Resonance Energy Transfer. Analytica. 2021.

Bortolomeazzi, M., et al. Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts. Gastroenterology. 2021.

Larijani, B., et al. Quantification of Biomarker Functionality Predicts Patient Outcomes. British Journal of Cancer. 2021.


Sanchez-Magraner, L., Miles, J., et al. High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to anti-PD-1/PD-L1 Treatment. Cancer Research. 2020.

2019 - 2014

Miles, J., et al. Time Resolved amplified FRET Identifies Protein Kinase B Activation State as a Poor Prognostic Marker in Clear Cell Renal Cell Carcinoma. BBA Clinical. 2017

Veeriah, S., et al. High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer. Cancer Research. 2014.


Miles, J., et al. The Fusion of Quantitative Molecular Proteomics and Immune-Oncology: A Step Towards Precision Medicine in Cancer Therapeutics. FEBS Letters. 2022.

Larijani, B., and Miles, J. Quantification of Protein-Protein Interactions and Activation Dynamics: A New Path to Predictive Biomarkers. Biophysics Chemistry. 2022.


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Learn about Quantifying Functions in Proteins (QF-Pro®) and how our advanced bio-imaging assay can further your research outputs. Find out about how QF-Pro® works and understand which protein functional events it can quantify.

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